Alzheimer's dementia is a devastating disease characterized by loss of normal thought parameters and memory that will strike one in ten over the age of 65 and nearly half by the time they reach 85. These scary statistics mean that virtually everyone will be touched in some way by this insidious illness at some point in their lives. A rapidly growing library of scientific evidence continues to emerge that demonstrates there are a number of lifestyle changes that we can make as young and middle-aged adults that can significantly lower our risk of developing Alzheimer's disease.

Researchers from the Barcelona Biomedical Research Institute in Spain publishing in the journal, Neurobiology of Aging have found that the combination of two neuroprotective therapies, voluntary physical exercise, and the daily intake of melatonin have been shown to have a synergistic effect against brain deterioration in several common variants of Alzheimer's disease.

The study's authors found that regular, voluntary exercise and daily intake of melatonin, both of which are known for the effects they have in regulating circadian rhythm, show a synergistic effect against brain deterioration that leads to the memory-robbing disease in a mouse model predisposed to develop the illness. Lead author, Dr. Coral Sanfeliu commented "For years we have known that the combination of different anti-aging therapies such as physical exercise, a Mediterranean diet, and not smoking adds years to one's life... now it seems that melatonin, the sleep hormone, also has important anti-aging effects."

Physical activity and melatonin dramatically lower the risk of Alzheimer's disease progression

To determine the effect of physical activity and melatonin supplementation on developing Alzheimer's dementia, researchers divided the genetically-predisposed mice into three control groups, and compared them to animals that had no known inclination to develop dementia. The animals were designated to undergo different treatment protocols including exercise by allowing unrestricted use of a running wheel, melatonin supplementation with a dose equivalent to 10 mg per kg of body weight, and a combination of melatonin and voluntary physical exercise.

After a period of six months, the study's authors concluded "The state of the mice undergoing treatment was closer to that of the mice with no mutations than to their own initial pathological state. From this we can say that the disease has significantly regressed." The genetically predisposed mice demonstrated a general improvement in behavior, learning, and memory with the three treatments. It should be noted that mice are commonly used for this type of research as they share similar neurobiology characteristics with humans.

Numerous prior studies have highlighted the importance of supplementation with melatonin (one to five milligrams, 30 minutes before bedtime) to encourage natural sleep rhythms, and to help lower risks from cancer and cardiovascular disease. We can now add the combination of regular physical activity and melatonin supplementation to the growing list of health benefits, as the therapy is shown to provide another potent tool in the battle to prevent Alzheimer's disease.

Sources:

http://www.neurobiologyofaging.org
http://www.sciencedaily.com/releases/2012/09/120926110110.htm
http://www.medicalnewstoday.com/releases/250741.php
http://www.eurekalert.org/pub_releases/2012-09/f-sf-mae092612.php

A genetic predisposition to Type II diabetes is found among more than half of the U.S. population. But if this form of the disease "runs" in your family, you can lower your risk by losing weight and exercising. However, Stanford University School of Medicine investigators have found a specific nutrient -- beta carotene -- may also impact the genetic risk and could offer protection from the disease.

The genomes of 50 to 60 percent of Americans carries two copies of a gene variant that raises the risk of Type II diabetes slightly but significantly. For the new study, just published in Human Genetics, the Stanford scientists searched for interactions between blood levels of various substances and these gene variants. People with a double dose of one of the predisposing-to-diabetes genes were found to have a statistically significant, inverse association of beta carotene blood levels to their Type II diabetes risk.

Simply put, the higher the level of beta carotene, a red-orange pigment abundant in plants and fruits that is related to vitamin A, the lower the risk of developing Type II diabetes.

The researchers also found a positive association between one form of vitamin E, gamma tocopherol, and a risk of Type II diabetes. Although you can expect some news reports will declare this means vitamin E is a cause of diabetes, let's look at exactly at what the Stanford scientists actually found. Only one form of vitamin E (which happens to be the major form found in the typical American diet of fast, processed foods), gamma tocopherol, was associated with a possible increased risk of Type II diabetes in people with high blood levels of the vitamin. Gamma tocopherol is found in processed foods like margarine and in soybean and corn oils.

Natural health advocates have long advised that mixed tocopherols are the healthy form of vitamin E most beneficial to the body. In fact, the Stanford study shows that blood levels of alpha tocopherol, another form of vitamin E that predominates in most supplements, produced no Type II diabetes-promoting interaction with the predisposing gene variant.

"Type II diabetes affects about 15 percent of the world's population, and the numbers are increasing," Atul Butte, MD, PhD, associate professor of systems medicine in pediatrics and senior author of the new study said in a media statement. "Government health authorities estimate that one-third of all children born in the United States since the year 2000 will get this disease at some point in their lives, possibly knocking decades off their life expectancies."

With the disease reaching epidemic proportions, obviously more research is needed into the protection from Type II diabetes specific nutrients provide. But it is clearly a sensible idea to eat more beta carotene-rich foods like carrots, beets and sweet potatoes, and/or to take beta carotene supplements.

In addition, as Natural News has covered before, along with exercise and weight control, scientists have found several other nutritional strategies can also help prevent and/or treat Type II diabetes. For example, research published in the journal Nature strongly indicates an imbalance of "good" versus "bad" bacteria in the intestinal tract appears to trigger Type II diabetes and taking probiotics may help prevent the disease. And Harvard School of Public Health investigators published their discovery in the Archives of Internal Medicine which reveals that eating two or more servings of brown rice per week slashes the risk of Type II diabetes.

Sources:

http://med.stanford.edu/ism/2013/january/butte.html

http://www.naturalnews.com

http://www.naturalnews.com/029143_brown_rice_diabetes.html

یاسین دارو قصد دارد با انجام بررسيهاي علمي بر روي بازار دارو و بهره گیری از سيستم‌هاي نوين بازاریابی، استفاده از فناوري اطلاعات به صورت فراگير، طراحي و اجراي فرآيندها و سيستم‌هاي مورد نياز، كاركنان متعهد و مجرب ، تتوان رقابت و ارايه محصولات و خدمات با كيفيت بالا را به صورت فزاينده‌اي افزايش دهد. ما در شركت یاسین دارو كه در زمينه تأمين و توزيع دارو فعاليت مي كنيم در صدد آن هستیم که با توسعه روز افزون توانمنديهاي سازماني و بهره گیری از کادری فعال و مجرب، بهترين كيفيت خدمات تولید و توزيع دارو و را در میهن عزیزمان و كشورهاي منطقه ارائه داده و بعنوان یکی از برترین و معتبرترين سيستم تأمين دارو شناخته شويم.