Pumpkin seeds are an edible seed typically roasted for consumption. They are a common ingredient in Mexican cuisine and are also often eaten as an individual snack. The seeds of the pumpkin are also commonly referred to as pepitas, Spanish for "little seed of squash."
This MNT Knowledge Center feature is part of a collection of articles on the health benefits of popular foods. It provides a nutritional breakdown of pumpkin seeds and an in-depth look at their possible health benefits, how to incorporate more pumpkin seeds into your diet and any potential health risks of consuming pumpkin seeds.
Nutritional breakdown of pumpkin seeds
According to the US Department of Agriculture (USDA) National Nutrient Database, approximately two tablespoons of unshelled pumpkin seeds (28 grams) contains 125 calories, 15 grams of carbohydrate (including 0 grams of sugar and 5 grams of fiber) and 5 grams of protein as well as 5% of your daily iron needs.
Pumpkin seeds are a source of magnesium, zinc, copper and selenium.
Possible health benefits of consuming pumpkin seeds
Pumpkin seeds with pumpkin and leaves.
Pumpkin seeds contain significant amounts of the macromineral magnesium.
Consuming fruits and vegetables of all kinds has long been associated with a reduced risk of many lifestyle-related health conditions.
Many studies have suggested that increasing consumption of plant foods like pumpkin seeds decreases the risk of obesity, diabetes, heart disease and overall mortality while promoting healthy complexion and hair, increased energy and overall lower weight.
The benefits of magnesium
Pumpkin seeds are exceptionally high in magnesium, one of the seven essential macrominerals. Two tablespoons of pumpkin seeds contain 74 mg of magnesium, about 1/4th of the daily recommended dietary allowance.
Magnesium plays an important role in over 300 enzymatic reactions within the body, including the metabolism of food and synthesis of fatty acids and proteins. Magnesium is involved in neuromuscular transmission and activity and muscle relaxation.
Magnesium deficiency, especially prevalent in older populations, is linked to insulin resistance, metabolic syndrome, coronary heart disease and osteoporosis.
Bone health
Magnesium is important for bone formation. High magnesium intakes are associated with a greater bone density and have shown to be effective for decreasing the risk of osteoporosis in postmenopausal women.
Diabetes
For every 100 mg/day increase in magnesium intake, the risk of developing type 2 diabetes decreases by approximately 15%. Low magnesium levels can impair insulin secretion and lower insulin sensitivity.
Heart health
Improvement in lipid profiles has been seen with an intake of 365 mg of magnesium per day.
Heart and liver health
Pumpkin seeds are rich in omega-3 and omega-6 fatty acids, antioxidants and fiber. This combination has benefits for both your heart and liver.1
The fiber in pumpkin seeds helps lower the total amount of cholesterol in the blood and decrease the risk of heart disease, while research to date suggests that omega-3s can decrease the risk for thrombosis and arrhythmias, which lead to heart attack, stroke and sudden cardiac death.
Omega-3s may also decrease LDL, total cholesterol and triglyceride levels, reduce atherosclerotic plaque, improve endothelial function and slightly lower blood pressure.
Insomnia prevention
A study published in Nutritional Neuroscience suggested that consuming tryptophan from a gourd seed alongside a carbohydrate source was comparable to pharmaceutical grade tryptophan for the treatment of insomnia.
Having a few pumpkin seeds before bed, with a small amount of carbohydrates such as a piece of fruit, may be beneficial in providing your body with the tryptophan needed for melatonin production.2
Pregnancy
It is estimated that over 80% of women worldwide have inadequate zinc intake.3 Low levels of zinc alter circulating levels of multiple hormones associated with the onset of labor. In addition to this, zinc is essential for normal immune function and prevention of uterine infections. All of these could potentially contribute to preterm birth.4
Fish oils come from fatty fish, also known as oily fish, specifically the tissue of fatty fish, such as trout, mackerel, tuna, herring, sardines, and salmon.
Fish oils are of interest to nutritionists and health care professionals because of two main ingredients: DHA (docosahexaenoic acid), and EPA (eicosapentaenoic acid) - both types of Omega-3 fatty acids.
The fillets of oily fish contain up to 30% oil; this figure may vary. White fish, on the other hand, only contain high concentrations of oil in the liver, and have much less oil. Apart from omega-3 fatty acids, oily fish are also good sources of vitamins A and D. Whitefish also contain these nutrients, but at much lower concentrations.
Health experts commonly tell people that oily fish have more health benefits than white fish. However, their recommendations have never been compellingly proven scientifically in large population studies.
Many health authorities around the world advise people to consume either plenty of oily fish or to take supplements, because of their supposed health benefits. Studies over the last ten years have produced mixed results regarding the benefits of the dietary intake of fish oils.
Possible health benefits of fish oils
Over the last ten years, there have been dozens of studies on fish oils and omega-3 oils. Some have backed up these claims, while others have not.
Fish oils are said to have several health benefits if they are included in a human diet, including:
Multiple sclerosis (MS)
Fish oils are said to help people with MS. However, a study carried out by researchers from University Hospital in Bergen, Norway, in April 2012 found that omega-3 fatty acids do not help people with MS.1
Prostate cancer
Fish oils reduce men's risk of developing prostate cancer if they follow a low-fat diet, one study found, while another linked omega-3 levels to a higher risk of aggressive prostate cancer2.
A study published in the Journal of the National Cancer Institute found that omega fish oils raise prostate cancer risk. The authors, from the Fred Hutchinson Cancer Research Center reported that high fish oil intake raises the risk of high-grade prostate cancer by 71% and all prostate cancers by 43%.3
Post-natal (post-partum) depression
Fish oils protect from post-partum depression - Dr. Michelle Price Judge, of the University of Connecticut School of Nursing, said after carrying out a study in 2011 "DHA consumption during pregnancy at levels that are reasonably attained from foods has the potential to decrease symptoms of postpartum depression."4
Mental health benefits
fish oils help young people with behavioral problems, especially those with ADHD.5
Memory benefits
Working memory can improve in healthy young adults if they increase their Omega-3 fatty acids intake, researchers reported in the journal PLOS One (October 2012 issue).6
Protection from Alzheimer's disease
Claims were made for many years that regular fish oil consumption would help prevent people from developing Alzheimer's disease. However, a major study in 2010 found that fish oils and a placebo were no different in Alzheimer's prevention.
In contrast, a study published in Neurology in 2007 reported that a diet in fish, omega-3 oils, fruit and veggies reduces dementia and Alzheimer's risk.7
Protection from vision loss
Adequate dietary consumption of DHA protects people from age-related vision loss, Canadian researchers reported in the journal Investigative Ophthalmology & Visual Science.8
Benefits for the fetus
omega-3 consumption boosts fetal cognitive and motor development - scientists from L'Université Laval Laval found that omega-3 consumption by the mother during her last three months of pregnancy improved her baby's sensory, cognitive and motor development.
Recently, Vitamin C has been forced into the backseat as other antioxidants have stood in the limelight. Vitamin C is the grandfather of antioxidants and it has clear health benefits.(1)
Dr. Ronald Hunninghake is well known for being an expert on this vitamin. He joined Dr. Hugh Riordan over twenty years ago and conducted research on I.V. administration of vitamin C for cancer patients. Though his clinic is the leading expert on vitamin C therapy for cancer, that hasn’t stopped others from completing similar research.(1)
New study builds on prior work of Dr. Hunninghake and shows that vitamin C kills colorectal cancer cells!
A recent study found that vitamin C could help fight colorectal cancer. The equivalency of vitamin C found in 300 oranges was found to kill colorectal cancer cells. Colorectal cancer is the third most common cancer in the United States. Approximately 50 percent of cases are more aggressive and do not respond to conventional therapies.(2)
The new study from Weill Cornell Medicine in New York discovered that in these cases, that high-dose vitamin C caused oxidation in the cancer cells and impaired the growth of the tumors.(2)
Vitamin C concentration equivalent to 300 oranges effective in causing oxidation of colorectal cancer cells and impairing growth of the tumor!
Vitamin C is generally thought to improve health because of its antioxidant effect, which prevents or delays some types of cell damage.(2)
The studies findings may also be helpful in treatment of renal cell carcinoma, bladder cancer and pancreatic cancer. The authors of the study report that that dosage would most likely need to be through I.V. as oral doses are not absorbed efficiently enough through the intestine.(2)
High doses of vitamin C do not absorb efficiently through the intestine and should be administered intravenously
Dr. Hunninghake recommends an average person take 1 gram of vitamin C twice per day. If you are suffering from chronic infections or fatigue you can gradually increase the does to a bowel tolerance dose. For most patient, oral dosages are fine but if you are fighting a serious illness, Dr. Hunninghake recommends I.V. vitamin C therapy.(1)
If you are seeking to increase vitamin C consumption through food, consider increasing your fruit and vegetable intake. Many eat oranges for their vitamin C content, but red and yellow bell peppers have the highest vitamin C coming in at 306 percent of daily value. Other fruits and vegetables are guavas, dark leafy greens, kiwi, broccoli, berries, tomatoes, peas, papaya, and of course oranges.(3)
As winter approaches, don’t forget about vitamin C! Start eating more fruits and vegetables and consider adding a high quality supplement. If you are battling cancer or another chronic disease, consider intravenous vitamin C therapy!
It is an effective pain reliever and has been linked to reduced risk of a number of health conditions, including heart attack, stroke and cancer. But is aspirin really the "wonder drug" many health experts claim it is?
Earlier this month, it was announced that researchers from the UK would be embarking on the biggest clinical trial of aspirin to date - the Add-Aspirin phase 3 trial - investigating whether the drug is effective for preventing cancer recurrence through a study of around 11,000 people.
The announcement has caused much excitement in the medical world, with many health experts claiming the trial could be "game-changing" if the drug is found effective, offering a non-expensive strategy to improve survival for cancer patients.
Cancer is just one in a long line of illnesses that aspirin may combat. But in the midst of potential health benefits comes a number of risks, a fact some health professionals believe is often overlooked.
"Because it's been around a long time people think 'it must be safe and it can't do me any harm,'" Prof. Peter Weissberg, medical director of the British Heart Foundation in the UK, told The Independent. "They are taking it 'just in case,' but it's much more dangerous than some other drugs which people get concerned about, like statins."
In this Spotlight, we take a closer look at the potential health benefits of aspirin, as well as the risks associated with the drug.
Aspirin: one of the most commonly used drugs worldwide
Aspirin is a drug that was developed by German research chemist Felix Hoffman, of pharmaceutical company Bayer, in 1897.
Hoffman created aspirin by developing a process to synthesize acetylsalicylic acid (ASA) - a synthetic derivative of a compound called salicin, which is found naturally in plants such as the willow tree.
Early clinical trials of aspirin found it was an effective treatment for pain, fever and inflammation. It is believed the drug produces these effects by inhibiting the production of pain-producing chemicals called prostaglandins. As such, aspirin is commonly used to help ease headache, muscle pain, toothaches and common colds, as well as swelling in arthritis.
More recently, however, researchers have discovered aspirin may also be an effective blood thinner, preventing the formation of blood clots in the arteries by blocking the production of a prostaglandin called thromboxane, which plays a key role in blood clotting.
As such, studies have shown daily aspirin therapy may lower the risk for heart attack and stroke, and it is often recommended for adults at high risk for these conditions.
The possible risks of aspirin use
However, as with any drug, there is a risk for side effects with regular aspirin use.
One of the most severe side effects of regular aspirin use is gastrointestinal bleeding, which can raise the risk of developing a stomach ulcer. If one already has a stomach ulcer, taking aspirin could cause further bleeding and be potentially life-threatening.
Aspirin may also interact with other drugs and increase risk of internal bleeding, particularly drugs with anti-clotting properties, such as warfarin, apixaban and dabigatran. Taking aspirin with some dietary supplements, such as evening primrose oil and fish oil, may also raise internal bleeding risk.
Some individuals are allergic to aspirin, with people who have asthma most at risk. An allergic reaction to the drug may cause swelling of the lips, mouth or throat, breathing problems and a skin rash.
Other side effects of aspirin include headache, nausea and vomiting, tinnitus and bruising.
Some studies have linked aspirin use with increased risk for other health conditions. In 2013, for example, a study published in JAMA Internal Medicine suggested long-term use of the drug may increase the risk of age-related macular degeneration - the primary cause of blindness among older adults.
Previous research has also linked aspirin use to greater risk for Reye's syndrome - a rare disorder characterized by swelling in the brain and liver, most common among children and teenagers.
Despite these potential risks, however, aspirin has become one of the most widely used over-the-counter drugs around the globe; more than 100 million standard aspirin tablets are produced every year.
But people are not just using the drug to relieve the odd headache or cold. It seems aspirin is growing in popularity as more people are taking the drug regularly with the aim of preventing numerous health conditions for which studies have suggested it is effective against.
Aspirin and heart health
As mentioned previously, one of the many benefits of aspirin is believed to be its ability to prevent the formation of blood clots.
Last year, Medical News Today reported on a study by researchers from Australia that found individuals with venous thromboembolism (VTE) - a condition comprised of deep vein thrombosis (blood clots in the legs) and pulmonary embolism (in which a blood clot breaks off and travels to the lungs) - saw a 42% reduction in blood clot recurrence with a 100-mg dose of aspirin daily.
This and numerous other studies hailing the anticoagulant properties of aspirin have led to recommendations that people at high risk for heart attack or stroke may benefit from daily aspirin therapy.
The American Heart Association (AHA), for example, recommend daily low-dose aspirin - under the instruction of a health care provider - for heart attack survivors and others at high risk of heart attack.
How to get perfect skin
We all suffer from bad skin days from time to time, but there are many tips and tricks you can use to get perfect skin naturally. To make spots and blemishes a thing of the past, check out these seven tips for clear skin.
Clear skin tip 1: Ditch the chemicals
It can be tempting to reach for chemical peels and ingredients such as salicylic acid to help clear up problem skin. However, many chemical-based skin products not only contain potentially harmful ingredients, they can also excessively dry out skin and exacerbate skin problems. For a gentler approach to fighting acne, opt for natural spot-fighting ingredients such as tea tree oil or manuka honey. Manuka honey not only has antimicrobial and antiseptic properties to fight spots, it also has the benefit of being able to reduce the scarring and marks left by spots.
Clear skin tip 2: Use spot-fighting makeup
We all know what it’s like to have a bad skin day when you just want to hide away under layers of makeup. However, while makeup can temporarily disguise the look of spots, it can also make the problem much worse. For confidence-boosting coverage that won’t cause flare-ups, make sure you opt for non-comedogenic makeup that won’t clog pores. To further increase the spot-fighting powers of your cosmetics, try using mineral makeup containing zinc oxide, which will fight against acne-causing bacteria.
Clear skin tip 3: Sip spearmint tea
Acne is generally caused by hormones called androgens, which can over-stimulate the sebaceous glands leading to oily skin, blocked pores and spots. To counteract these effects, oral contraceptives are often prescribed to women suffering from acne. However, while beneficial for clearing spots, these contraceptive pills can have inconvenient and even dangerous side effects. Luckily, research suggests that spearmint tea has similar anti-androgen properties, which could help reduce acne and hormone imbalances in women.
Clear skin tip 4: Reduce your skin’s contact to bacteria
You may be surprised at how often your skin comes into contact with dirt and germs that can lead to acne. During the time you are asleep, your pillow comes into contact with makeup, skin oils and saliva, making it a breeding ground for bacteria that can worsen acne. Likewise, unwashed makeup brushes can spread bacteria to your skin. To minimise your skin’s contact to bacteria, make sure you wash makeup brushes every two weeks and change your pillowcase regularly. Also, avoid touching your face as much as possible and clean your phone with antibacterial wipes before making calls.
Clear skin tip 5: Cleanse your skin properly
If you suffer from oily or acne-prone skin it can be tempting to over-cleanse your skin to dry out oils and kill bacteria. However, cleansing your skin too frequently or using harsh cleansers can dry out your skin, causing flakiness which can clog pores. It can also cause your skin to produce more oils to compensate. Instead, wash your skin twice a day with a gentle, PH-neutral cleanser so as not to destroy the acid mantle of the skin, which protects against moisture loss and bacteria. Remove the cleanser with a muslin cloth to lightly exfoliate the skin.
Clear skin tip 6: Change your diet
Eating a balanced diet with plenty of nutrients and antioxidants is one of the key factors behind beautiful looking skin. However, there are also certain foods you can cut back on or eat more of in order to help get rid of spots. Research suggests that dairy is a major precursor of acne for many people due to the hormones it contains. Plastic water bottles and food packaging can also leach out chemicals which can lead to hormone imbalance. Swap packaged foods for fresh, skin-friendly produce including lots of fruit and vegetables and foods rich in omega-3 fatty acids.
Clear skin tip 7: Find ways to deal with stress
Research findings published in the journal Archives of Dermatology suggest that high stress levels can significantly worsen acne. It is thought that this may be due to the fact that stress stimulates the production of hormones which stimulate oil production in the skin’s sebaceous glands. Stress is also thought to instigate the release of chemicals which can lead to inflammation. To help keep your skin clear and spot-free, try to find healthy ways to deal with stress such as exercise, meditation or pampering. Try to talk through problems with someone else as well to help relieve any worries.
Supplements aren't for everyone, but older adults and others may benefit from specific supplements.
By Mayo Clinic Staff
The Dietary Guidelines for Americans make it clear that your nutritional needs should be met primarily through your diet.
For some people, however, supplements may be a useful way to get nutrients they might otherwise be lacking. But before you go shopping for supplements, get the facts on what they will and won't do for you.
Supplements vs. whole foods
Supplements aren't intended to be a food substitute because they can't replicate all of the nutrients and benefits of whole foods, such as fruits and vegetables. So depending on your situation and your eating habits, dietary supplements may not be worth the expense.
Whole foods offer three main benefits over dietary supplements:
Greater nutrition. Whole foods are complex, containing a variety of the micronutrients your body needs — not just one. An orange, for example, provides vitamin C plus some beta carotene, calcium and other nutrients. It's likely these compounds work together to produce their beneficial effect.
Essential fiber. Whole foods, such as whole grains, fruits, vegetables and legumes, provide dietary fiber. Most high-fiber foods are also packed with other essential nutrients. Fiber, as part of a healthy diet, can help prevent certain diseases, such as type 2 diabetes and heart disease, and it can also help manage constipation.
Protective substances. Whole foods contain other substances important for good health. Fruits and vegetables, for example, contain naturally occurring substances called phytochemicals, which may help protect you against cancer, heart disease, diabetes and high blood pressure. Many are also good sources of antioxidants — substances that slow down oxidation, a natural process that leads to cell and tissue damage.
Who needs supplements?
If you're generally healthy and eat a wide variety of foods, including fruits, vegetables, whole grains, legumes, low-fat dairy products, lean meats and fish, you likely don't need supplements.
However, the dietary guidelines recommend supplements — or fortified foods — in the following situations:
Women who may become pregnant should get 400 micrograms a day of folic acid from fortified foods or supplements, in addition to eating foods that naturally contain folate.
Women who are pregnant should take a prenatal vitamin that includes iron or a separate iron supplement.
Adults age 50 or older should eat foods fortified with vitamin B-12, such as fortified cereals, or take a multivitamin that contains B-12 or a separate B-12 supplement.
Adults age 65 and older who do not live in assisted living or nursing homes should take 800 international units (IU) of vitamin D daily to reduce the risk of falls.
Dietary supplements also may be appropriate if you:
Don't eat well or consume less than 1,600 calories a day.
Are a vegan or a vegetarian who eats a limited variety of foods.
Don't obtain two to three servings of fish a week. If you have difficulty achieving this amount, some experts recommend adding a fish oil supplement to your daily regimen.
Are a woman who experiences heavy bleeding during your menstrual period.
Have a medical condition that affects how your body absorbs or uses nutrients, such as chronic diarrhea, food allergies, food intolerance, or a disease of the liver, gallbladder, intestines or pancreas.
Have had surgery on your digestive tract and are not able to digest and absorb nutrients properly.
Talk to your doctor or a dietitian about which supplements and what doses might be appropriate for you. Be sure to ask about possible side effects and interactions with any medications you take.
Choosing and using supplements
If you decide to take a vitamin or mineral supplement, consider these factors:
Check the label. Read labels carefully. Product labels can tell you what the active ingredient or ingredients are, which nutrients are included, the serving size — for example, capsule, packet or teaspoonful — and the amount of nutrients in each serving.
Avoid megadoses. In general, choose a multivitamin-mineral supplement that provides about 100 percent of the Daily Value (DV) of all the vitamins and minerals, rather than one which has, for example, 500 percent of the DV for one vitamin and only 20 percent of the DV for another.
Check expiration dates. Dietary supplements can lose potency over time, especially in hot and humid climates. If a supplement doesn't have an expiration date, don't buy it. If your supplements have expired, discard them.
Watch what you eat. Vitamins and minerals are being added to a growing number of foods, including breakfast cereals and beverages. If you're also taking supplements, you may be getting more than you realize of certain nutrients. Taking more than you need is expensive and can raise your risk of side effects. For example, too much iron can cause nausea and vomiting and may damage the liver and other organs.
Keep up with supplement safety alerts
The Food and Drug Administration (FDA) keeps a list of dietary supplements that are under regulatory review or that have been reported to cause adverse effects. If you're taking a supplement, it's a good idea to check the FDA website periodically for updates.