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Yaghoot Rooyan International Group proudly introduce itself as one of the most reliable and active groups in marketing and supplying cosmetic and hygienic products, pharmaceutical and food supplements, prostheses from valid foreign companies and manufactures according to national standards ...

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Mr. Seyed Hosein Etemadi Monfared ,PhD,the founder of Yaghoot Rooyan Holding Group announced that the Ministry Of Health and Medical Sciences (MOH) issued the permission of principled agreement for constructing the pharmaceutical raw material manufacturing factory.
“ this permission is issued under the name of Sepid Teb Nia International Co. as one the subsets of Yaghoot Rooyan Holding group after the  legal committee of assessment of Eligibility for production and import of drugs and Biologic Materials study and confirmation” Mr. Etemadi added while noting this issue.
He declared that the Supplements and Specific Foods of MOH has agreed with the pharmaceutical raw material import under the name of Nano Sepid Farmed Co. as another subsets of Yaghoot Rooyan Holding Group and added “these macro- projects based on this permission are aimed to promote the supply chain of pharmaceutical raw material and cooperate with internal and overseas industries and drug research centers emphasizing communication system with manufacturers.

Mr. Etemadi, PHD, also said that Hasti Daroo Darman international Co. as one of the Yaghoot Rooyan Holding Group also could obtain the principled agreement for establishment of co-laboratory in the field of Hygienics and cosmetics, food supplements, and specialized laboratories for hair color from technical committee of assessment and approval of allowed laboratories inside the country. So this company can observe the realization of new processes according to the last research and scientific achievements from now on.

The Yaghoot Rooyan Holding Group founder also expressed at the final part of his press conference “one of the most outstanding achievements of this Holding is obtain the permission for production of some food supplements such as Beta caroten, B12, L-citrolin,L-Ajenine and many other kinds of drugs under the name of Sepid Teb Nia International Co. from Ministry Of Health and Medical Sciences and also the permission for production special establishment, designing and assembling some of the Hygienic and cosmetic products under the name of Asal Daroo Kish International Co. from the ministry of industry, mine and commerce . we proud of all these achievements.”

Researches of scientists of Oklahoma have revealed that fundamental cells, extracted from lipid tissue during liposuction process may be used for development of new blood vessels of low diameter, used in by-pass surgery and other processes accordingly.
Millions of patients, suffering from cardiovascular disorders do need grafting thin vessels for the processes, which do require return of blood to blocked vessels.  The vessels obtained from liposuction, which are developed in laboratories, may help solve the main problems, associated with grafting of blood vessels from other parts of body or artificial vessels, which are not live tissues.
The said researches have changed fundamental cells, obtained from lipid to soft muscular cells at laboratory and then, they develop the said cells on a thin membrane of Collagen, which has been devised inside a tube as much as a tiny blood vessel.
Researchers hope that they would be able to test the said prefabricated samples of the said technology on animals in the next six months.
The said research has been presented in scientific conferences of basic sciences of cardiology of American Heart Association.

Mr. Seyed Hosein Etemadi Monfared ,PhD,the founder of Yaghoot Rooyan Holding Group announced that the Ministry Of Health and Medical Sciences (MOH) issued the permission of principled agreement for constructing the pharmaceutical raw material manufacturing factory.
“ this permission is issued under the name of Sepid Teb Nia International Co. as one the subsets of Yaghoot Rooyan Holding group after the  legal committee of assessment of Eligibility for production and import of drugs and Biologic Materials study and confirmation” Mr. Etemadi added while noting this issue.
He declared that the Supplements and Specific Foods of MOH has agreed with the pharmaceutical raw material import under the name of Nano Sepid Farmed Co. as another subsets of Yaghoot Rooyan Holding Group and added “these macro- projects based on this permission are aimed to promote the supply chain of pharmaceutical raw material and cooperate with internal and overseas industries and drug research centers emphasizing communication system with manufacturers.

Mr. Etemadi, PHD, also said that Hasti Daroo Darman international Co. as one of the Yaghoot Rooyan Holding Group also could obtain the principled agreement for establishment of co-laboratory in the field of Hygienics and cosmetics, food supplements, and specialized laboratories for hair color from technical committee of assessment and approval of allowed laboratories inside the country. So this company can observe the realization of new processes according to the last research and scientific achievements from now on.

The Yaghoot Rooyan Holding Group founder also expressed at the final part of his press conference “one of the most outstanding achievements of this Holding is obtain the permission for production of some food supplements such as Beta caroten, B12, L-citrolin,L-Ajenine and many other kinds of drugs under the name of Sepid Teb Nia International Co. from Ministry Of Health and Medical Sciences and also the permission for production special establishment, designing and assembling some of the Hygienic and cosmetic products under the name of Asal Daroo Kish International Co. from the ministry of industry, mine and commerce . we proud of all these achievements.”

 

 

 


McGill researchers have shown that melatonin supplements may make bones stronger in old rats. This suggests a possible avenue for the prevention of osteoporosis. Bones are built up by certain cells known as osteoblasts during the daytime and broken down by others (osteoclasts) at night. As we age, we sleep less, and so the cells that break down the bones are more active.  By giving old rats melatonin supplements to regulate their circadian rhythms, the McGill researchers have been able to make their bones denser, less brittle and more flexible. Next step is to explore whether melatonin supplements prevent bone breakdown or can actually repair damage.

Research on elderly rats suggests possible avenue for prevention of osteoporosis

Faleh Tamimi, a professor in McGill's School of Dentistry, is the leader of a research team that has just discovered that melatonin supplements make bones stronger in elderly rats and therefore, potentially, in elderly humans too. "Old rats are tedious to work with because they get sick a lot and that means they also cost a lot more. But if you're interested in diseases like osteoporosis, they're an essential part of the process."

Dem bones, dem bones, dem dry bones - sleep and bone regulation

The process of bone breakdown and buildup is affected by our circadian rhythms. The cells which break down our bones (known as osteoclasts) are more active at night, while those responsible for bone formation (osteoblasts) are more active during daylight hours. "As we age, we sleep less well, which means that the osteoclasts are more active," says Tamimi. "This tends to speed up the process of bone breakdown."

It is already well established that melatonin plays a role in regulating our body clocks and can potentially help us sleep better. So the researchers suspected that a melatonin supplement would help regulate the circadian rhythms of the elderly rats, thus reducing the activity of the osteoclasts and slowing down the process of bone breakdown. And that is exactly what they found.



The researchers found that there was a significant increase in both bone volume and density among the rats that had received melatonin supplements. As a result, it took much more force to break the bones of rats that had taken the melatonin supplements, a finding that suggests to the researchers that melatonin may prove a useful tool in combatting osteoporosis.

For Tamimi and his colleagues the next big question is whether melatonin is preventing or actually reversing the process of bone breakdown. "Until there is more research as well as clinical trials to determine how exactly the melatonin is working, we can't recommend that people with osteoporosis go ahead and simply take melatonin supplements," says Tamimi. "I am applying for funding to pursue the research and we hope to have answers soon."

 

 

 

 

 

 

itamin D supplementation could be a safe and cost-effective treatment strategy for individuals with multiple sclerosis, according to new research published in the journal Neurology.

Researchers found a high daily dose of vitamin D for 6 months reduced MS-related T cell activity in patients with the disease.

Numerous studies have associated low levels of vitamin D with increased risk of multiple sclerosis (MS). Additionally, among people who have MS, low vitamin D levels have been linked to greater disability and more severe symptoms.

Whether vitamin D supplementation may benefit patients with MS, however, has been a subject of debate.

With the aim of finding out, study coauthor Dr. Peter A. Calabresi, of Johns Hopkins University School of Medicine in Baltimore, MD, and colleagues analyzed the effects of vitamin D supplementation among 40 adults aged 18-55 with relapsing-remitting MS.

Each individual took either 10,400 IU (high dose) or 800 IU (low dose) of vitamin D3 supplements daily for 6 months. For comparison, the standard recommended daily vitamin D intake for adults aged 18-70 is 600 IU.

At study baseline and at 3 and 6 months, the vitamin D levels of each participant were measured through blood tests, and the researchers also assessed subjects' MS-related T cell responses - an indicator of disease activity.
High-dose vitamin D reduced MS-related T cell activity

The study results revealed that individuals who took the high dose of vitamin D3 demonstrated a reduction in the percentage of T cells associated with MS activity.

Specifically, the researchers found that when vitamin D levels in the blood reached greater than 18 nanograms per milliliter (ng/ml), each further 5 ng/ml rise in vitamin D levels was linked to a 1% fall in the percentage of interleukin-17 T cells in the blood; these cells are believed to play a role in MS pathogenesis.

No reduction in the percentage of interleukin-17 T cells in the blood was identified among individuals who took the low dose of vitamin D3.

There were no differences in side effects from vitamin D supplementation between the high-dose and low-dose groups, according to the researchers, and one person from each group experienced a disease relapse.

Though MS incidence and prevalence is not currently tracked in the US, it is estimated that around 400,000 Americans are living with the condition and around 200 new cases are diagnosed each week.

At present, there is no cure for MS; symptoms and the course of disease are normally managed through medications. But according to Dr. Calabresi, these latest findings indicate there may be a promising new treatment option for MS:

    "These results are exciting, as vitamin D has the potential to be an inexpensive, safe and convenient treatment for people with MS.

    More research is needed to confirm these findings with larger groups of people and to help us understand the mechanisms for these effects, but the results are promising."

 

 

 


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