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Feature

Food and Drug Administration of America has confirmed generating the first vaccine for cancer, which entered into a new era of treatment of cancers all over the world.
This vaccine, under the name of “Provenge” has been generated, aiming at treatment of prostate cancer. The said vaccine has been used during clinical test periods and, compared to placebos, the said vaccine could increase lifetime of patients for four months. This medicine is not regarded as a procedure for treatment or prevention of the respective disease and it is not similar to the vaccines, which have been generated for treatment of measles or Hepatitis. But, it is regarded as a treatment vaccine. It means that the said vaccine may improve immunity system of patients.  Ten samples of vaccines have been generated for treatment of cancer so far. However, “Provenge” vaccine is the first sample, which has been confirmed by FDA. Non-confirmation of the said medicine had led to severe objection of patients and investors for about three years. The said vaccine is manufactured for each patient according to an order placed for this purpose. It means that while blood globules of a patient are collected and specific immunity cells are extracted from the said cells accordingly. Then, final cells are injected to the patient for three times within a one-month period. The said vaccines costs 93,000.- Dollars. Common treatment procedures of cancer namely radiotherapy, chemotherapy and even prostatectomy shall cause many damages to patients. Thus, a medicine, which is able to stimulate and to improve natural body immunity system of patients may be regarded a valuable replacement for the said procedures. Extent of side-effects of the said vaccine is too limited including fever, fatigue and pain. According to the report of Pop Science, Provenge Vaccine is used for the patients, who suffering from prostate cancer, with metastasis to their entire body. In 2009, National Cancer Institute of America reported about 192000 new cases of Prostate Cancer. About 27000 patients out of the said cases died due to the said disease.

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An English Company is going through the process of obtaining a license to use a new vaccine, which prevents development of Meningitis- Type B. This Company has claimed that the said vaccine will be presented to the word in near future.
As reported by reporter for the site of Borderless Physicians, Meningitis is an inflammation of myelin and cerebral membrane, affecting most of the adolescences with a mortality of 14-15%. Many patients, who have recovered, are affected by permanent neural injuries or have lost their hearing forever.
Certain vaccines have been produced in order to campaign against Meningitis of types A and C. However, none of the said vaccines has been effective for Meningitis of Type B. Meningitis of Type A is the most prevalent type of the said disease in Africa.
Meningitis of Type B is the most common type of the said complication in Europe. This fatal disease kills one out of ten patients, who suffer from the said complication. Even if the said disease is treated, 1/5th of those patients who had this kind of disease suffer from neural or hearing complications forever.
On average, 1870 cases of Meningitis of Type B are reported ever year in England. 200 cases out of total reported ones die due to the said disease. Half of those who die because of this type of Meningitis are kids, who are below five years.
Furthermore, over 400 kids, suffering from the said disease are affected by severe complications namely impairment, blindness, deafness, and cerebral injuries.
Although it has been reported that vaccination plans for campaign against other types of Meningitis were successful in England, presently, there is no vaccine against Meningitis of Type B in the nation.
Meningo Cocci B or Meningitis of Type B is the most prevalent type of bacterium meningitis in England. This type of Meningitis is regarded as the most fatal diseases as well.
Since there are many varieties of Meningitis of Type B, producing respective vaccine, which could prevent development of the said disease is a difficult task.
Bexsero is the first vaccine, which prevents development of the fatal type of Meningo Cocci B, which in some cases leads to death only within a few hours.
European Medical Institute which supervises over a supervising organization of medicines in England has stated its auspicious decision to use the aforesaid vaccine. Thus, it so seems that this vaccine is effective and using the same is not dangerous either.
This is the first step, taken in confirming procedure of the said vaccine. According to the said report, authorization for use of the said vaccines will be issued within the next three months accordingly.

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Scientists have produced a kind of headband. One may put this specific kind of headband on his/her forehead for 30 days every day in order to prevent migraine headaches.
This tool, which is called Cefaly, transmits electrical pulses to the nerve above eye bowel, controlling the sense inside and surrounding the eye.
As reported by Mehr, according to a study, of which results have been published in Neurology Journal, researchers have found that disabling headaches of the individuals who use this specific kind of headband have been decreased by about 1/3rd .
Using the said headband, number of individuals, whose migraine headaches have been reduced by 1/2nd , has been tripled.
Professor Jean Shonen, from Belgium University, stated: “This specific kind of headband is devised across the forehead and the patient must use the said headband for 20 minutes every day”. As stated by the above-named, this treatment causes side-effects.
The above-named researcher further added: “The results obtained from this fresh treatment method are too much similar to the medicines, prescribed for prevention of occurrence of migraine headaches. However, the said medicines usually cause many side-effects and eventually, the patients have to stop using the said medicines.
In this study, 67 persons, with four migraine seizures on average per month have been studied for four months, receiving no treatment.
The candidates were divided into two groups. One group was stimulated by electrical pulses for three months, 20 minutes every day. The second group was treated for the similar period, using a device (a device with electrical pulses of low or no effect).
Researchers have found that these underwent real irritation, number of days during which they suffer from migraine headaches has been decreased by 1/3 per month. It means that number of such days has been reached from seven to five days while no changes have been observed in another group using device.

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Researchers of medical sciences are of this opinion that respective results of a research done on a few patients, suffering from colorectal cancer has shown that decrease of mortality only occurs by prescribing Aspirin for a group of patients, suffering from colorectal cancer. It should be noted that a mutation has been identified in CA3PIK gene of the aforesaid patients.
As reported by the reporter for the site of Borderless Physicians, Aspirin or “Acetylsalicylic Acid” is the highly-appreciated medicines all over the globe. Every year, 50,000 Millions of tablets of Aspirin are consumed through the world.
Following a 12-year research, researchers further added that during said period prescribing Aspirin to the patients, suffering from colorectal cancer, with such genetic mutation, described earlier, has decreased mortality caused by the said kind of cancer by 80%, compared to those patients, who have not taken the said medicine.
In Britain, every individual consumes 70 tables of Aspirin together with other pain killers, Caffeine or Vitamin C.
Further to its property as a pain killer, Aspirin is also a medicine used as refrigerant and anti-inflammation medicine. Moreover, consuming Aspirin has also indicated such side-effects as gastric ulcers and prevents blood clotting.
However, nowadays Aspirin is used in the following cases:
Prevention of cardiac disorders by 37.6%, arthritis by 23.3%, headache by 12.2%, body pains by 12.2% and other pains by 14.1%.
Other results obtained from this research reveal that this dropping trend of mortality has not been observed among other individuals, receiving Aspirin, but with no such genetic mutation as described earlier.
Colon and rectum cancer, which is also known as Colorectal Cancer, is the second main cause of death caused by cancers among men and the third main cause of death caused by cancers among women. On a whole, the five-year survival for colorectal is given as 58%, compared to other cancers, which are diagnosed at primary stages given as 89%.
It should be noted that following an appropriate diet such as eating low fat foods, eating fibers, fruits and vegetables as well as doing physical activities may prevent development of colorectal cancer.
The results obtained from the said research have been published in New England Medical Journal Accordingly.

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A sub-specialist in cornea pointed that application of the new method of Femto-LASIK for treatment of cornea diseases and especially for correction of eye refractive disorders, and further added: “Using this kind of laser, surgeries on cornea is done more precisely and quickly in such a way as such operation takes less than one minute and the patient is able to resume his work the day after this surgery. Dr Seyed Javad Hashemian stated on the new method of Femto-LASIK used for treatment of cornea diseases: Femto-LASIK is one of the most modern method for correction of myopia and hyperopia as well as astigmatism. Femtosecond laser enjoys various applications in ophthalmology including making incisions on cornea, treatment of glaucoma and some complications with retina.
He further added: “Presently, this new system has been devised in many specialized eye hospitals. This kind of laser, with a length of 1053 is in the range of infrared lights. It is able to pass through various spaces, making incisions on each axle. Consequently, this kind of laser has helped us make kinds of surgical incisions on all directions and axles.
He further added: “Nowadays, this method is used in surgeries on cornea such as layer grafting and the surgeries, which does require that a stent be devised in cornea thickness. This stent is also used for correction of refractive disorders through a flap (making in incision on cornea). Respective advantages of the said surgery, which is done by the help of Femtosecond laser are namely more preciseness, less complications and high speed”. Stating that previously during provision method of flap using LASIK, error coefficient could have caused that the said flap lacks desirable quality and appearance”. He also stated: “However, such problems as described above have been removed now because accuracy of the said device in preparing the said flap is really at higher level and it is controllable as it has been made considering cornea cut cellulose structure. Thus, respective surgery may be design and performed proportionate to conditions of each patient.
The above-named sub-specialist in cornea has also emphasized on the fact that complications of such surgeries have decreased to a large extent and he added: “This method is useful especially for those who are not able to go through other methods including surface cornea laser, P.R.P and LASEK.    He also stated: “There are different methods, used for correction of refractive disorders. However, in the patients, who are candidates for LASIK surgery, the said operation shall be performed more precisely and reliably using femtolaser equipment”.

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Researches of scientists of Oklahoma have revealed that fundamental cells, extracted from lipid tissue during liposuction process may be used for development of new blood vessels of low diameter, used in by-pass surgery and other processes accordingly.
Millions of patients, suffering from cardiovascular disorders do need grafting thin vessels for the processes, which do require return of blood to blocked vessels.  The vessels obtained from liposuction, which are developed in laboratories, may help solve the main problems, associated with grafting of blood vessels from other parts of body or artificial vessels, which are not live tissues.
The said researches have changed fundamental cells, obtained from lipid to soft muscular cells at laboratory and then, they develop the said cells on a thin membrane of Collagen, which has been devised inside a tube as much as a tiny blood vessel.
Researchers hope that they would be able to test the said prefabricated samples of the said technology on animals in the next six months.
The said research has been presented in scientific conferences of basic sciences of cardiology of American Heart Association.

Feature

An anti-cancer medicine of “Taxotere”, has been produced at laboratory quantities, thanks to unsparing efforts of researchers and professors of Research Institute of Medicinal Raw Materials and Herbals of Shahid Beheshti University.
As reported by scientific service of ISNA, Docetaxel under the name of “Taxotere”, is one of the mostly consumed and the most expensive medicines of high frequency, used for control and treatment of such cancers as ovaries, prostates, breast, lungs and the ones.  
Presently, over 6 kilograms of the said medicine, equivalent of 50,000,000.- Dollars  is used in Iran. The said medicine is exclusively produced by a limited number of countries.
“Docetaxel is a semi-synthetic D amide, similar to Paklitaxel (a similar medicine), which is synthesized from a precursor material, derived from the leaves of  Taxus Bacca tree.
Presently, all production stages of the said medicine including synthesis and purification are done at laboratory quantity at Research Institute of Medicinal Raw Materials and Herbals of Shahid Beheshti University and it is possible to present the said medicine to pharmaceutical industry accordingly.

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Chronic venous insufficiency is the main cause of Varicose Veins disease. While chronic venous insufficiency (CVI) is the most prevalent cause for leg pain and its inflation, this insufficiency occurs when venous valves lack the required performance and blood circulation in leg is impaired.
20% of adults suffer from this disease and on this basis the number of women is higher than men.
In this new treatment method, the disabled value is replaced with an efficient implant.
At the present time, this implant is not prepared to be used in the patients' bodies and it is in the trial phase.
In case this implant is put into practice, most vascular diseases can be treated through this method.
It should be mentioned that Erbaven Retard is one of the highly popular products of Yaghout Company. Besides causing positive effects in those patients suffering from varicose veins, this product has also been effective in the re-health of feet.

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In a new achievement the American scientists have successfully manufactured a new manual system which injects a small ice bell under the skin and in this way it prevents from pain transmission in the patients suffering from arthritis.
The effect of this outpatient treatment which takes less then a few minutes is similar to local anesthetics; however, it has a longer effect.
Now the scientists have began a larger trial by using this method and have tested that on the patients suffering from knee arthritis.
When cartilages at the end of bones are destroyed as the result of abrasion, bones overlap and experience friction causing pain.
One out of each adult suffers from knee arthritis. Treatments for this pain encompass a range of steroid injections and calmatives to surgery and replacement of joints.
This system is called Cryo-Touch system and is a non-surgical approach which removes pharmaceutical need.
This icy treatment is a kind of Cryotherapy in which physicians use very cold temperatures to treat different diseases.
This treatment is used for different skin diseases including freezing of small skin cancers and benign tumors such as wart.
Cryotherapy is also used to treat prostate cancer in which physicians freeze cancer cells.
Researchers have recently used this method for the pain of joints especially in elbow, knee and shoulder.
This modern system that has been approved for use in UK is constituted of three stainless steel needles which are connected to a cylinder containing fluid nitrogen oxide.
These needles are designed to prevent from transmission of this very cold material into tissues which may cause serious injuries in case of contact.
Instead, when the fluid exits from the needle, it will change into gas due to very high pressure. This causes the needle to become very cold and an icy ball is produced on its top. In this system, three needles are used to increase the icy ball volume.
These needles are plunged within a few millimeters under the skin. Then, the system starts and a small icy ball is formed under the skin.
This icy ball damages to the blood vessels that transmit blood to the peripheral nerves around the joint. These nerves cannot send pain signs without any blood source.
Each treatment takes about 5 minutes. The physician lets the icy ball to become warm and then pulls out the needles.
A former human research conducted by the University of Washington with a similar technology showed that this treatment was effective for some patients and its effect remained for eight months.
The pain returns with the growth of new blood vessels and reactivation of nerves. In such case, another injection period may be effective.

Feature

دو محقق ایتالیایی با اعمال تغییرات ژنتیکی در گیاهان کاسنی تلخ، قهوه و نارگیل موفق به ساخت مولکول ضد سرطان شدند.

به گزارش منابع خبری ایتالیا، ˈمیرکو فانلیˈ و ˈویئری فوزیˈ از دانشگاه ˈاوربینوˈ موفق شدند از طریق تغییرات ژنتیکی در این گیاهان مولکولی بسازند که باعث کاهش عمر سلول های سرطانی و در نهایت خودکشی آنها شود.

این دو که یکی بیولوژیست و دیگری شیمیدان است موفق به تغییر ژنتیکی مولکولی بنام ˈمالتولوˈ شدند که معمولا به عنوان افزودنی غذایی استفاده می شود.

این مولکول قادر است ژن سلول های سرطانی را تغییر دهد که موجب کاهش عمر آنها و در نهایت نوعی خودکشی سلول سرطانی شود.

محققان ایتالیایی در آزمایش های خود در آزمایشگاه به این نتیجه رسیدند که مولکول مذکور سلول های سرطانی را نمی کشد بلکه آنها را به خودکشی سوق می دهد.

تحقیقات مذکور می تواند در آینده کمک با ارزشی برای مقابله با سلول های سرطانی و برای ساخت داروهای جدید باشد.

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دانشمندان استرالیایی 28 ناحیه DNA انسان را که با بیماری فشارخون بالا مرتبط است، شناسایی کردند.

به گزارش نشریه ˈهلث دی نیوزˈ، پزشکان استرالیایی به تازگی با مطالعه روی بخش هایی از توالی رشته DNA انسان دریافتند، مؤلفه های موجود در 28 ناحیه از DNA انسان با بیماری فشارخون بالا کاملا مرتبط می باشد.

براساس این گزارش، نتایج این مطالعه نشان می دهد، سه ناحیه از 28 ناحیه شناسایی شده، دارای ژن هایی هستند که موجب دفع سدیم توسط کلیه ها و انبساط عروقی در شریان ها شده و از طریق این دو مکانیزم فشارخون بالا را در افراد متعادل می کند.

این گزارش می افزاید: این ژن ها جزئی از سیستم (CGMP) بدن بوده و نقش بسیار مهمی در کنترل فشارخون دارد.

به گزارش پایگاه خبری وزارت بهداشت، درمان و آموزش پزشکی، کشف این نواحی در DNA و ژن های مرتبط با فشارخون بالا انواع روش های جدید درمان فشارخون بالا در آینده را امکان پذیر می کند.

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نخستین چشم مصنوعی جهان، تاکنون امکان به دست‌آوردن دوباره بخشی از بینایی را برای بیش از 24 بیمار اروپایی فراهم کرده است.

به گزارش سرویس فناوری خبرگزاری دانشجویان ایران (ایسنا)، سازمان غذا و داروی امریکا جدیداً این چشم مصنوعی را تایید کرده و کمپانی سازنده، Second Sight Medical Products، امکان فروش آن به بیماران امریکایی را دارد.

چشم جدید «سیستم پروتز شبکیه آرگوس 2» نام دارد.

نابینایان پس از دریافت پروتز بیونیکی، قادر شدند بدون استفاده از عصا، فردی را که از خیابان می‌گذشت، ببینند و همچنین انحنای خیابان را بدون استفاده از عصا تشخیص دهند.

«آرگوس 2» دارای سه بخش است: یک بخش شامل یک دوربین ویدئوی کوچک است که بر روی عینک‌های آفتابی قرار گرفته است.

بخش دوم یک رایانه قابل‌حمل است که می‌توان آن را بر روی کمربند نصب یا در کیف پول حمل کرد.

پیچیده‌ترین قسمت این سیستم، ایمپلنت ریز است که طی یک عمل جراحی دو ساعته، نزدیک شبکیه کاشته شده و این حامل 60 الکترود است.

رایانه سیگنال‌های دریافتی از دوربین ویدیوئی را پردازش و به طور بی‌سیم اطلاعات را به ایمپلنت‌ها بازچینش می‌کند.

چشم بیونیکی یک فرایند تولید غیرمعمول را می‌طلبد ؛ فرآیندی که در آن، مهندسان بسیار متبحر به منظور اتصال هر یک از آرایه 60 الکترود، به طور دستی با میکروسکوپ‌هایی کار می‌کنند.

تقریبا تمامی مراحل تولید این چشم، زیر میکروسکوپ انجام شده است.

عرض خطوط موجود بر روی ایمپلنت‌های عنبیه، فقط 25 میکرون یا یک هزارم عرض یک اینچ هستند.

بهای این چشم مصنوعی جدید 100 هزار دلار امریکا گزارش شده است.

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محققان دانشگاه ایالتی فلوریدا موفق به توسعه یک نانو قطار دی ان ای شدند که در درمان انواع سرطان کاربرد دارد.

به گزارش روز شنبه خبرنگار گروه علمی ایرنا به نقل از پایگاه خبری ˈرویترزگ، با استفاده از این روش DNA nanotrainمی توان در کمترین زمان ممکن سلول های سرطانی را شناسایی و به آنها دارورسانی کرد.

بیماری سرطان در سال های اولیه هیچ علامتی ندارد و بیمار زمانی از بیماری خود مطلع می شود که سلول های سرطانی اکثر اندام داخلی را آلوده کرده اند.

پس از شناسایی سرطان، پزشکان وارد مرحله درمان می شوند. درمان انوان سرطان با استفاده از شیمی درمانی صورت می گیرد.

داروهای شیمی درمانی بسیار قوی هستند و معمولا اثرات مضری را به دنبال دارند.

انواع روش های درمانی اعم از شیمی درمانی و رادیوتراپی دقت بالایی ندارند و فقط روی سلول های بیمار تاثیر نمی گذارند بلکه سلول های سالم مجاور را نیز تخریب می کنند و بدن بیمار هر روز ضعیف تر می شود.

در این روش نوین فقط خود سلول های سرطانی در معرض اصابت دارو قرار می گیرند و هیچ آسیبی به سلول های سالم وراد نمی شود.

مدیر این پروژه تحقیقاتی می گوید که درمان به روش نانو قطار نسبت به روش های مشابه ساده تر و ارزان تر است و با دقت بیشتری انجام میشود.

در این روش برخلاف سایر روش های مشابه از نانو ذرات مضر برای بدن استفاده نمی شود و تمام ذرات ارگانیک هستند.